Any non-syndromic pontocerebellar hypoplasia in which the cause of the disease is a mutation in the SEPSECS gene. The disease is pontocerebellar hypoplasia type 2D (Monarch Disease Ontology term MONDO_0013438). Also known as: SEPSECS non-syndromic pontocerebellar hypoplasia, non-syndromic pontocerebellar hypoplasia caused by mutation in SEPSECS.