MONDO_0013523 (Nestor-Guillermo progeria syndrome) is a premature aging syndrome, autosomal recessive, characterized by lipoatrophy, osteoporosis, and very severe osteolysis. Patients have no cardiovascular impairment, diabetes mellitus, or hypertriglyceridemia, but suffer profound skeletal abnormalities that affect their quality of life. Also known as: BANF1-related neurodevelopmental syndrome, NGPS.