Monarch Disease Ontology id MONDO_0013576 (recurrent infections associated with rare immunoglobulin isotypes deficiency) is deficiencies in immunoglobulin (Ig) isotypes (including: isolated IgG subclass deficiency, IgG subclass deficiency with IgA deficiency and kappa chain deficiency) are primary immunodeficiencies that are often asymptomatic but can be characterized by recurrent, often pyogenic, sinopulmonary infections. Also known as: IgG subclass deficiency with IgA subclass deficiency, isolated IgG subclass deficiency, kappa-chain deficiency.