Any hereditary nonpolyposis colon cancer in which the cause of the disease is a mutation in the TGFBR2 gene. The disease is colorectal cancer, hereditary nonpolyposis, type 6 (MONDO_0013695). Also known as: TGFBR2 hereditary nonpolyposis colon cancer, hereditary nonpolyposis colon cancer caused by mutation in TGFBR2.