MEGF10-related myopathy (MONDO_0013731, a Monarch Disease Ontology identifier) is a congenital myopathy caused by mutations in the multiple epidermal growth factor-like domains 10 (MEGF10) gene, which causes early-onset myopathy characterized by severe weakness, scoliosis, joint contractures, areflexia, respiratory distress, and dysphagia, and a milder phenotype of minicore myopathy. Also known as: MEGF10 myopathy, congenital myopathy 10A, severe variant.