An instance of systemic lupus erythematosus (disease) that is caused by mutations in DNASE1L3. The disease is autosomal systemic lupus erythematosus type 16 (MONDO_0013743). Also known as: SLEB16, systemic lupus erythematosus 16, systemic lupus erythematosus related to DNASE1L3, systemic lupus erythematosus type 16.