Any hereditary spastic paraplegia in which the cause of the disease is a mutation in the TECPR2 gene. The disease is MONDO_0014016 (hereditary spastic paraplegia 49). Also known as: SPG49, TECPR2 hereditary spastic paraplegia, autosomal recessive spastic paraplegia 49, autosomal recessive spastic paraplegia type 49, hereditary spastic paraplegia caused by mutation in TECPR2, hereditary spastic paraplegia type 49, neuropathy, hereditary sensory and autonomic, type IX, with developmental delay.