Any central precocious puberty in which the cause of the disease is a mutation in the MKRN3 gene. The disease is Monarch Disease Ontology term MONDO_0014137 (precocious puberty, central, 2). Also known as: MKRN3 central precocious puberty, central precocious puberty caused by mutation in MKRN3, precocious puberty, central, type 2.