Severe combined immunodeficiency due to IKK2 deficiency is a rare, genetic form of primary immunodeficiency characterized by life-threatening bacterial, fungal and viral infections with the onset in infancy, and failure to thrive. Typically, hypogammaglobulinemia or agammaglobulinemia and normal levels of T and B cells are present. The disease is MONDO_0014267 (severe combined immunodeficiency due to IKK2 deficiency). Also known as: SCID due to IKK2 deficiency, immunodeficiency 15B, immunodeficiency type 15.