MONDO_0014282 (hereditary spastic paraplegia 72) is any pure hereditary spastic paraplegia in which the cause of the disease is a mutation in the REEP2 gene. Also known as: REEP2 pure hereditary spastic paraplegia, SPG72, autosomal spastic paraplegia type 72, hereditary spastic paraplegia type 72, pure hereditary spastic paraplegia caused by mutation in REEP2.