Any isolated congenital breast hypoplasia/aplasia in which the cause of the disease is a mutation in the PTPRF gene. The disease is breasts and/or nipples, aplasia or hypoplasia of, 2 (MONDO_0014450). Also known as: PTPRF isolated congenital breast hypoplasia/aplasia, breasts and/or nipples, aplasia or hypoplasia of, type 2, isolated congenital breast hypoplasia/aplasia caused by mutation in PTPRF.