Any Charcot-Marie-Tooth disease in which the cause of the disease is a mutation in the IGHMBP2 gene. The disease is Charcot-Marie-Tooth disease axonal type 2S (MONDO_0014511). Also known as: CMT2S, Charcot-Marie-Tooth disease caused by mutation in IGHMBP2, Charcot-Marie-Tooth disease type 2S, Charcot-Marie-Tooth neuropathy type 2S, IGHMBP2 Charcot-Marie-Tooth disease, autosomal recessive axonal Charcot-Marie-Tooth type 2S.