Any isolated hereditary giant platelet disorder in which the cause of the disease is a mutation in the PRKACG gene. The disease is MONDO_0014518 (platelet-type bleeding disorder 19). Also known as: BDPLT19, PRKACG isolated hereditary giant platelet disorder, isolated hereditary giant platelet disorder caused by mutation in PRKACG, severe autosomal recessive macrothrombocytopenia.