amyotrophic lateral sclerosis type 22 (MONDO_0014531, a Monarch Disease Ontology term) is any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the TUBA4A gene. Also known as: ALS 22, TUBA4A amyotrophic lateral sclerosis, amyotrophic lateral sclerosis 22, amyotrophic lateral sclerosis 22 with or without frontotemporal dementia, amyotrophic lateral sclerosis caused by mutation in TUBA4A.