Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the UNC45B gene. The disease is cataract 43 (MONDO_0014565, a Monarch Disease Ontology identifier). Also known as: CTRCT43, UNC45B early-onset non-syndromic cataract, cataract type 43, early-onset non-syndromic cataract caused by mutation in UNC45B.