Any leukodystrophy in which the cause of the disease is a mutation in the VPS11 gene. The disease is Monarch Disease Ontology id MONDO_0014732 (hypomyelinating leukodystrophy 12). Also known as: HLD12, VPS11 leukodystrophy, VPS11-related autosomal recessive hypomyelinating leukoencephalopathy, hypomyelinating leukodystrophy type 12, leukodystrophy caused by mutation in VPS11, leukodystrophy, hypomyelinating, 12, leukodystrophy, hypomyelinating, type 12.