Monarch Disease Ontology term MONDO_0014844 (premature ovarian failure 12) is any primary ovarian failure in which the cause of the disease is a mutation in the SYCE1 gene. Also known as: POF12, SYCE1 primary ovarian failure, premature ovarian failure 12; POF12, premature ovarian failure type 12, primary ovarian failure caused by mutation in SYCE1.