Arachnodactyly-intellectual disability-dysmorphism syndrome is characterized by moderate intellectual deficit, brachycephaly, typical facies (thin lips and microstomia), ectomorphic habitus with extremely long, thin fingers and toes, and hypoplastic external genitalia. It has been described in three patients. The disease is arachnodactyly-intellectual disability-dysmorphism syndrome (MONDO_0015235, a Monarch Disease Ontology identifier). Also known as: De Die-Smulders-Vles-Fryns syndrome, die Smulders Vles Fryns syndrome.