diazoxide-resistant diffuse hyperinsulinism (MONDO_0015625) can be described as follows. Diazoxide-resistant diffuse hyperinsulism (DRDH) is a form of Diazoxide resistant hyperinsulinism characterized by recurrent episodes of profound hypoglycemia caused by an excessive/ uncontrolled insulin secretion (inappropriate for the level of glycemia) due to diffuse involvement of pancreas that is unresponsive to medical treatment with diazoxide, often necessitating near total/total pancreatectomy. Also known as: hyperinsulinemic hypoglycemia, diazoxide-resistant diffuse form.