Type 2N von Willebrand disease (type 2N VWD) is a subtype of type 2 VWD characterized by a bleeding disorder associated with a marked decrease in the affinity of the Willebrand factor (von Willebrand factor; VWF) for factor VIII (FVIII). The disease is Monarch Disease Ontology entry MONDO_0015631 (von Willebrand disease type 2N). Also known as: von Willebrand disease Normandy variant, von Willebrand disease, type 2N.