An extremely rare form of bone dysplasia characterized by the features of osteogenesis imperfecta such as bone fragility associated with multiple fractures, bone deformities (metaphyseal irregularities and bowing of the long bones) and blue sclera, in association with growth failure, craniosynostosis, hydrocephalus, ocular proptosis, and distinctive facial features (e.g. frontal bossing, midface hypoplasia, and micrognathia). The disease is Monarch Disease Ontology term MONDO_0016085 (Cole-Carpenter syndrome). Also known as: bone fragility-craniosynostosis-proptosis-hydrocephalus syndrome.