Deficiencies or mutations in the genes for the sarcoglycan complex subunits. A variety of phenotypes are associated with these mutations including a subgroup of autosomal recessive limb girdle muscular dystrophies, cardiomyopathies, and respiratory deficiency. The disease is MONDO_0016140 (sarcoglycanopathy). Also known as: qualitative or quantitative defects of sarcoglycan.