A group of muscle diseases with basis in CAV3, which encodes caveolin-3, a muscle-specific membrane protein and the principal component of caveolae membrane in muscle cells in vivo. It is the only gene in which pathogenic variants are known to cause caveolinopathies. Sequence analysis identifies pathogenic variants in more than 99% of affected individuals. The disease is caveolinopathy (MONDO_0016146, a Monarch Disease Ontology identifier). Also known as: qualitative or quantitative defects of caveolin-3.