Adult hepatocellular carcinoma is the most common primary liver cancer of adulthood. Derived from well-differentiated hepatocytes, it often develops from chronic liver cirrhosis which is most often due to hepatitis B and C virus or alcohol abuse. Symptoms are hepatic mass, abdominal pain and, in advanced stages, jaundice, cachexia and liver failure. The disease is adult hepatocellular carcinoma (MONDO_0016216). Also known as: adult HCC, adult hepatoma, adult primary carcinoma of liver cell, adult primary carcinoma of the liver cell, adult primary hepatocellular carcinoma, adult primary hepatoma, adult primary liver cell carcinoma, hepatocellular carcinoma of adults.