A genetically and clinically heterogeneous inherited disorder characterized by digital clubbing and osteoarthropathy, with variable features of pachydermia, delayed closure of the fontanels, and congenital heart disease. There are two types of PHO: pachydermoperiostosis and cranio-osteoarthropathy. The disease is primary hypertrophic osteoarthropathy (Monarch Disease Ontology entry MONDO_0016620). Also known as: PDP, PHO, Touraine Solente Gole syndrome, Touraine-Solente-Gole syndrome, hypertrophic osteoarthropathy, primary, hypertrophic osteoarthropathy, primary, autosomal recessive, type 1, hypertropic osteoarthropathy, primary, idiopathic hypertrophic osteoarthropathy.