Autosomal dominant optic atrophy and peripheral neuropathy (ADOAPN) is a form of autosomal dominant optic atrophy (ADOA), characterized by progressive and isolated visual loss in the first decade of life, decreased reflexes in the lower limbs and a mild cerebellar stance. The disease is autosomal dominant optic atrophy and peripheral neuropathy (Monarch Disease Ontology entry MONDO_0016646).