pineoblastoma (MONDO_0016722) is a rare, malignant type of supratentorial primitive neuroectodermal tumor (sPNET), found mainly in children (less than 10% of cases are reported in adults), and located in the pineal region of the brain but that can metastasize along the neuroaxis. As it is the most aggressive of the pineal parenchymal tumors, it is usually associated with a poor prognosis. Also known as: PNET of pineal gland, PNET of the pineal gland, pineal PNET, pineal gland PNET, pineal gland primitive neuroectodermal neoplasm, pineal gland primitive neuroectodermal tumor, pineal gland primitive neuroectodermal tumour, pineal primitive neuroectodermal neoplasm.