A malignant germ cell tumor of the central nervous system characterized by extra-embryonic differentiation along trophoblastic lines. The diagnosis requires the identification of cytotrophoblastic elements, as well as syncytiotrophoblastic giant cells. (WHO). The disease is choriocarcinoma of the central nervous system (MONDO_0016740, a Monarch Disease Ontology term). Also known as: central nervous system choriocarcinoma, central nervous system choriocarcinoma (disease), choriocarcinoma of CNS, choriocarcinoma of the CNS.