MONDO_0016862 (Alagille syndrome due to a JAG1 point mutation) is any Alagille syndrome due to a variation in the JAG1 gene that affects many organ systems including the liver, heart, skeleton, eyes and kidneys. Also known as: Alagille syndrome type 1, Alagille syndrome-JAG1, Alagille-Watson syndrome due to a JAG1 point mutation, arteriohepatic dysplasia due to a JAG1 point mutation, syndromic bile duct paucity due to a JAG1 point mutation.