Chromosome 16p duplication is a chromosome abnormality that occurs when there is an extra copy of genetic material on the short arm (p) of chromosome 16. The severity of the condition and the signs and symptoms depend on the size and location of the duplication and which genes are involved. Features that often occur in people with chromosome 16p duplication include developmental delay, intellectual disability, behavioral problems and distinctive facial features. Most cases are not inherited, but people can pass the duplication on to their children. Treatment is based on the signs and symptoms present in each person. The disease is MONDO_0016949 (partial duplication of the short arm of chromosome 16). Also known as: partial duplication of chromosome 16p, partial duplication of the short arm of chromosome type 16, partial trisomy of chromosome 16p, partial trisomy of the short arm of chromosome 16.