acute myeloid leukemia with CEBPA somatic mutations (MONDO_0017894, a Monarch Disease Ontology identifier) is a subtype of acute myeloid leukemia with recurrent genetic abnormalities, characterized by clonal proliferation of myeloid blasts harboring somatic mutations of the CEBPA gene in the bone marrow, blood and, rarely, other tissues. It can present with anemia, thrombocytopenia, and other nonspecific symptoms related to ineffective hematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement (gingivitis, splenomegaly). Also known as: AML with CEBPA somatic mutations, AML with mutated CEBPA, acute myeloid Leukaemia with mutated CEBPA, acute myeloid Leukaemia with non-germline mutated CEBPA, acute myeloid Leukemia with mutated CEBPA, acute myeloid Leukemia with non-germline mutated CEBPA, non-familial acute myeloid leukaemia with mutated CEBPA, non-familial acute myeloid leukemia with mutated CEBPA.