Trigonocephaly-broad thumbs syndrome is characterized by neonatal trigonocephaly and multiple anomalies including craniosynostosis, shallow orbits, unusual nose, deviation of the terminal phalanges of fingers 1, 2, and 5, and broad toes with duplication of the terminal phalanx. It has been described in a mother and her son. It is transmitted as an autosomal dominant trait. The disease is Monarch Disease Ontology term MONDO_0018064 (trigonocephaly-broad thumbs syndrome). Also known as: Hunter-Rudd-Hoffmann syndrome.