CADDS (Monarch Disease Ontology id MONDO_0018247) is a rare, genetic, neurometabolic disease characterized by severe intrauterine growth retardation, failure to thrive, profound neonatal hypotonia, severe global development delay, elevated very long chain fatty acids in plasma, and neonatal cholestasis leading to hepatic failure and death. Other features include ocular abnormalities (e.g. blindness and cataracts), sensorineural deafness, seizures, and abnormal brain morphology (notably delayed CNS myelination and ventriculomegaly). Also known as: Zellweger-like contiguous gene deletion syndrome, contiguous ABCD1 DXS1357E deletion syndrome.