A disease caused by the fungus Histoplasma capsulatum. It primarily affects the lungs but can also occur as a disseminated disease that affects additional organs. The acute respiratory disease has symptoms similar to those of a cold or flu and it usually resolves without treatment in healthy individuals. The disseminated form is generally fatal if untreated. The disease is MONDO_0018312 (histoplasmosis). Also known as: Histoplasma caused disease or disorder, Histoplasma disease or disorder, Histoplasma infectious disease, darling disease.