A clinicopathologic variant of multicentric Castleman's disease characterized by thrombocytopenia, ascites (anasarca), microcytic anemia, myelofibrosis, renal dysfunction, and organomegaly. The disease is Monarch Disease Ontology entry MONDO_0018702 (Castleman-Kojima disease). Also known as: TAFRO syndrome, thrombocytopenia-anasarca-fever-renal insufficiency-organomegaly syndrome.