Congenital hypopituitarism is characterized by multiple pituitary hormone deficiency, including somatotroph, thyrotroph, lactotroph, corticotroph or gonadotroph deficiencies, due to mutations of pituitary transcription factors involved in pituitary ontogenesis. The disease is MONDO_0018762 (non-acquired combined pituitary hormone deficiency). Also known as: congenital combined pituitary hormone deficiency, congenital hypopituitarism.