A form of lysosomal acid lipase deficiency characterized by progressive cholesterol esters and triglyceride accumulation in tissues and organs typically presenting with hepatosplenomegaly, liver dysfunction and/or dyslipidemia. The disease is cholesteryl ester storage disease (Monarch Disease Ontology identifier MONDO_0019149). Also known as: LAL deficiency, partial, LIPA deficiency, partial, cholesterol ester hydrolase deficiency, partial, cholesterol ester storage disease, lysosomal acid lipase deficiency, partial.