MONDO_0019266 (SAPHO syndrome) (acronym for Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis) is an auto-inflammatory disease, mainly characterized by the association of neutrophilic cutaneous involvement and chronic osteomyelitis. Also known as: PPHS, Pustulo-psoriatic hyperostotic Spondyloarthritis, synovitis, acne, pustulosis palmaris, hyperostosis, osteomyelitis syndrome, synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome, synovitis-acne-pustulosis-hyperostosis-osteitis syndrome.