Monarch Disease Ontology id MONDO_0019347 (peeling skin syndrome) (PSS) refers to a group of rare autosomal recessive forms of ichthyosis that is characterized clinically by superficial, asymptomatic, spontaneous peeling of the skin and histologically by a shedding of the outer layers of the epidermis. PSS presents with either an acral (acral PSS) or a generalized distribution (generalized PSS type A (non inflammatory) or B (inflammatory)). Some cases remain difficult to classify, suggesting that there could be additional subtypes of PSS. Also known as: PSS, deciduous skin, familial continuous skin peeling syndrome, idiopathic deciduous skin, keratosis exfoliativa congenita, peeling skin disease.