Monarch Disease Ontology entry MONDO_0019455 (acute panmyelosis with myelofibrosis) is an acute myeloid leukemia characterized by bone marrow fibrosis without preexisting primary myelofibrosis. Also known as: APMF, acute (malignant) myelofibrosis, acute (malignant) myelosclerosis, acute myelodysplasia with myelofibrosis, acute myelofibrosis, acute myelosclerosis, acute panmyelosis.