Complete androgen insensitivity syndrome (CAIS) is a form of androgen insensitivity syndrome (AIS), a disorder of sex development (DSD), characterized by the presence of female external genitalia in a 46,XY individual with normal testis development but undescended testes and unresponsiveness to age-appropriate levels of androgens. The disease is complete androgen insensitivity syndrome (Monarch Disease Ontology entry MONDO_0021023). Also known as: CAIS, complete androgen resistance syndrome.