A spectrum of malignant tumors, affecting mostly males under age 20, characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. These tumors may occur in the soft tissues or the bones. Pain and the presence of a mass are the most common clinical symptoms. The disease is Monarch Disease Ontology term MONDO_0021038 (Ewing sarcoma/peripheral primitive neuroectodermal tumor). Also known as: EFTs, Ewing family of tumors, Ewing family of tumours, Ewing sarcoma family of tumors, Ewing sarcoma family of tumours, Ewing sarcoma/peripheral PNET, Ewing's family of tumors, Ewing's family of tumours.