von Willebrand disease (hereditary or acquired) (MONDO_0024574) is hereditary or acquired coagulation disorder characterized by a qualitative or quantitative deficiency of the von Willebrand factor. The latter plays an important role in platelet adhesion. Signs and symptoms include bruises, nose bleeding, gum bleeding following a dental procedure, heavy menstrual bleeding, and gastrointestinal bleeding. Also known as: VWD, Von Willebrand Disease, von Willebrand disorder, von Willebrand's disease.