An inflammatory bowel disease characterized by abdominal pain and watery or bloody diarrhea, with changes in the intestinal tract consistent with Crohn disease that has material basis in heterozygous mutation in the CARD8 gene on chromosome 19q13.33. The disease is inflammatory bowel disease 30 (MONDO_0033643). Also known as: IBD30, inflammatory bowel disease (Crohn disease) 30.