acute myeloid leukemia with mutated NPM1 (MONDO_0044923) is an acute myeloid leukemia with mutation of the nucleophosmin gene. It is usually associated with normal karyotype and frequently has myelomonocytic or monocytic features. It usually responds to induction therapy. Also known as: AML with mutated NPM1, AML, Mutation of the Nucleophosmin Gene, AML, NPM1 Mutation, AML, NPM1 gene mutation, AML, Nucleophosmin Gene Mutation, NPMc+ AML, acute myeloid leukaemia with cytoplasmic nucleophosmin, acute myeloid leukemia with cytoplasmic nucleophosmin.