Monarch Disease Ontology entry MONDO_0060582 (auditory neuropathy-optic atrophy syndrome) is a mitochondrial dysfunction syndrome in which the cause of the disease is a mutation in the FDXR gene. It is characterized by onset of visual and hearing impairment in the first or second decades. Also known as: ANOA, auditory neuropathy and optic atrophy, multiple mitochondrial dysfunctions syndrome 9A.