Monarch Disease Ontology term MONDO_0100389 (acute myeloid leukemia, Trisomy 8) is any acute myeloid leukemia that has the chromosomal anomaly Trisomy 8. (A chromosomal abnormality consisting of the presence of a third copy of chromosome 8 in somatic cells.). Also known as: AML, Trisomy 8, AML, tri8.