PRKAG2-related cardiomyopathy (Monarch Disease Ontology entry MONDO_0800484) is a metabolic heart condition characterized by variable cardiac hypertrophy, ventricular pre-excitation, and aberrant glycogen storage in the cardiac tissue due to a pathogenic variant in PRKAG2 that results in a net anabolic effect in cardiac cells. Also known as: PRKAG2 cardiac syndrome, PRKAG2 cardiomyopathy, PRKAG2 syndrome.