A rare congenital disease caused by a mutation in the UBA2 gene, charcterized by scalp defects, digital and skeletal anomalies, early growth deficiency, and neurodevelopmental delay. Ectrodactyly presents in some cases. The disease is ACCES syndrome (MONDO_0859262, a Monarch Disease Ontology identifier). Also known as: UBA2-related neurodevelopmental disorder, aplasia cutis congenita with ectrodactyly skeletal syndrome, aplasia cutis congenita with ectrodactyly skeletal syndrome.