Monarch Disease Ontology term MONDO_0958106 (congenital insensitivity to pain syndrome, Marsili type) is a pain insensitivity disorder in which the cause of the disease is a mutation in ZFHX2 gene. It is characterized by a lowered ability to sense pain, to experience temperature, and to sweat. Also known as: MARSILI syndrome, MARSIS, Marsili syndrome, congenital analgesia, autosomal dominant, indifference to pain, congenital, autosomal dominant, insensitivity to pain, congenital, autosomal dominant.